Immuno-Oncology
Explore immune response with spatial biology insights
The tumor microenvironment (TME) represents a complex landscape of cancerous, normal and immune cells within diverse cellular neighborhoods and niches. Understanding the spatial dynamics of cells and tissues and their interplay is crucial for comprehending and treating cancer and requires advanced imaging technologies capable of capturing multiparametric spatial data at high throughput.
Now, researchers can interrogate the TME with the fastest, most comprehensive approach by using new whole slide imaging modes for Imaging Mass Cytometry™ (IMC™), enabling high-multiplex imaging to advance immuno-oncology studies.
Standardized panels to easily interpret tissue heterogeneity
Quickly develop a deep understanding of cancer-related processes in the tumor microenvironment with human- and mouse-specific panels that enable detection of tumor-infiltrating lymphocytes, immune activation and tissue architecture.
Human Immuno-Oncology
The Human Immuno-Oncology IMC Panel, 31 Antibodies combines overall tissue architecture, cell interaction and single-cell phenotypic and functional markers in the single largest Imaging Mass Cytometry panel currently available.
Mouse Immuno-Oncology
The 28-plex Maxpar® OnDemand™ Mouse Immuno-Oncology IMC Panel Kit consists of four modules that offer comprehensive cellular and tissue phenotyping capabilities to understand the structure and function of normal and diseased mouse tissues.
Let us do the work for you.
Did you know Standard BioTools™ has an in-house service lab? Send us your samples and we will send you the data.
New in IMC for immuno-oncology
Reveal Heterogeneity of Tumors With Whole Slide Imaging
This application note highlights the capability of IMC whole slide imaging together with ready-to-go human immuno-oncology IMC panels to provide streamlined and extensive evaluation of the human tumor microenvironment. This fast and comprehensive approach means researchers can quickly capture biological insights across the whole tumor at the single-cell level.
Co-detection of RNA and protein
Deciphering the spatial arrangement of cell types within the TME could be crucial in empowering the next immuno-oncology breakthroughs. Co-detection of RNA and protein using IMC is a novel approach that enables interrogation of gene expression specific to a cell type of interest and identification of the source of a secreted protein, all in the context of the spatial landscape.
IMC Trending Topics in Immuno-Oncology
This article covers the latest research and past publications using IMC to explore the tumor-immune landscape, biomarker discovery and methods associated with therapeutics development.
Immuno-oncology e-book
In this e-book, two articles selected from the Drug Target Review highlight findings that researchers believe could be used to enhance immunotherapies. This is supplemented with a short Expert View article on using IMC to accelerate success in cancer immunotherapy development.
Expert insight on the transformation of precision medicine
Olivier Elemento, PhD
Professor, Physiology and Biophysics, Weill Cornell Medicine
Director, Englander Institute for Precision Medicine
Oliver Elemento shares his expert insight on the transformation of precision medicine. In this short video, Elemento describes why artificial intelligence, high-throughput sequencing and Imaging Mass Cytometry are becoming increasingly critical tools for personalizing treatments and improving patient outcomes.
Learn about the multi-collaborative Tumor Profiler Study
Read the Cancer Cell article Tumor Profiler Study: Integrated multi-omic, functional tumor profiling for clinical decision support and hear Bernd Bodenmiller discuss his lab’s role in this multi-site collaborative project. The author suggests how technologies like IMC could be used to contribute to oncological clinical decision-making in the future.
Customer Stories
Learn more about how our customers are leveraging Standard BioTools™ technology
Corinne Ramos, PhD, MBA
Advancing drug development with molecular imaging
Yongpan Yan, PhD
An approach that combines molecular biology, immunology and cell biology tools to uniquely
Xianting Ding, PhD
High-dimensional single-cell analysis enhances precision medicine
Bernd Bodenmiller, PhD
Bernd Bodenmiller on revealing new insights into tumors with Imaging Mass Cytometry
RELATED BLOG POSTS
-
Deciphering one of the most challenging forms of cancer
A poster by Standard BioTools scientists sheds light on the spatial landscape of neoplastic brain tissue
-
Harness the power of mouse tumor models
How to enable studies that reveal significant details of tumor development, progression and treatment
Unless explicitly and expressly stated otherwise, all products are provided for Research Use Only, not for use in diagnostic procedures. Find more information here.